Date published: 2025-12-13

1-800-457-3801

SCBT Portrait Logo
Seach Input

11-deoxy Prostaglandin F (CAS 37786-06-4)

0.0(0)
Write a reviewAsk a question

Application:
11-deoxy Prostaglandin F is a more potent, synthetic analog of PGF
CAS Number:
37786-06-4
Molecular Weight:
338.5
Molecular Formula:
C20H34O4
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

QUICK LINKS

A synthetic analog of PGF2α. It is a more potent agonist than PGF2α at inducing smooth muscle contractions of rabbit aorta, guinea pig trachea, and dog saphenous vein.1 It is approximately 20% less potent than U-46619.1


11-deoxy Prostaglandin F,[object Object], (CAS 37786-06-4) References

  1. Activin-A in myometrium: characterization of the actions on myometrial cells.  |  Ciarmela, P., et al. 2008. Endocrinology. 149: 2506-16. PMID: 18239071
  2. 11-deoxy prostaglandin F(2α), a thromboxane A2 receptor agonist, partially alleviates embryo crowding in Lpar3((-/-)) females.  |  Ye, X., et al. 2012. Fertil Steril. 97: 757-63. PMID: 22222195
  3. Selective Small Molecule Activators of TREK-2 Channels Stimulate Dorsal Root Ganglion c-Fiber Nociceptor Two-Pore-Domain Potassium Channel Currents and Limit Calcium Influx.  |  Dadi, PK., et al. 2017. ACS Chem Neurosci. 8: 558-568. PMID: 27805811
  4. Terbinafine is a novel and selective activator of the two-pore domain potassium channel TASK3.  |  Wright, PD., et al. 2017. Biochem Biophys Res Commun. 493: 444-450. PMID: 28882594
  5. Molecular determinants of chemical modulation of two-pore domain potassium channels.  |  Şterbuleac, D. 2019. Chem Biol Drug Des. 94: 1596-1614. PMID: 31124599
  6. Pranlukast is a novel small molecule activator of the two-pore domain potassium channel TREK2.  |  Wright, PD., et al. 2019. Biochem Biophys Res Commun. 520: 35-40. PMID: 31564414
  7. Two-Pore Domain Potassium Channels as Drug Targets: Anesthesia and Beyond.  |  Mathie, A., et al. 2021. Annu Rev Pharmacol Toxicol. 61: 401-420. PMID: 32679007
  8. Pathophysiological Role of K2P Channels in Human Diseases.  |  Lee, LM., et al. 2021. Cell Physiol Biochem. 55: 65-86. PMID: 33667332
  9. Aprepitant is a novel, selective activator of the K2P channel TRAAK.  |  McCoull, D., et al. 2022. Biochem Biophys Res Commun. 588: 41-46. PMID: 34942533
  10. Antagonism of the thromboxane-sensitive contractile systems of the rabbit aorta, dog saphenous vein and guinea-pig trachea.  |  Jones, RL., et al. 1982. Br J Pharmacol. 76: 423-38. PMID: 6286023

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

11-deoxy Prostaglandin F, 1 mg

sc-204963
1 mg
$60.00

11-deoxy Prostaglandin F, 5 mg

sc-204963A
5 mg
$272.00