Date published: 2025-12-13

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2-Chloro-6-methylquinoline-3-carboxaldehyde (CAS 73568-27-1)

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CAS Number:
73568-27-1
Purity:
96%
Molecular Weight:
205.64
Molecular Formula:
C11H8ClNO
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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2-Chloro-6-methylquinoline-3-carboxaldehyde is a synthetic compound utilized in scientific research to investigate biological processes. Its mechanism of action involves forming covalent adducts with nucleophilic amino acids, particularly cysteine and lysine residues, allowing for protein and peptide modification and labeling. This property makes it a valuable reagent for studying protein structure and function, protein-protein interactions, and post-translational modifications. Researchers employ this compound to investigate enzyme catalysis, protein folding, and cellular signaling pathways, as well as to develop novel bioconjugation methods and affinity probes. It reacts with specific amino acid residues, enabling the study of protein function and interactions. This compound has been applied in various research areas, including biochemistry, molecular biology, and cell biology, to advance our understanding of biological systems.


2-Chloro-6-methylquinoline-3-carboxaldehyde (CAS 73568-27-1) References

  1. Synthesis and pharmacological evaluation of some new 4-thiazolidinone derivatives[J].  |  Kaneria D J, Datta N J, Khunt R C. 2003,. Indian Journal of Heterocyclic Chemistry,. 12(3):: 277-278.
  2. Synthesis of meso-tetrakis (2-chloroquinolin-3-yl) porphyrins[J].  |  Amaravathi M, Babu M M, Chandramouli G. 2007,. Arkivoc,. 2007(1):: 148-53.
  3. Synthesis and Thermal degradation kinetics of Co (II), Ni (II), Cd (II), Zn (II), Pd (II), Rh (III) and Ru (III) complexes with methylquinolino [3, 2-b] benzoxazepine[J].  |  Basavaraju B, Naik H S B. 2007. JOURNAL OF TEACHING AND RESEARCH IN CHEMISTRY,., 14(1).: 8.
  4. An economical nucleophilic route toward facile synthesis of pyrano [4, 3-b] quinolin-1-ones via 6-endo-dig cyclization of o-alkynylquinoline esters[J].  |  Sharma N, Asthana M, Nandini D,. 2013. Tetrahedron,., 69(7):: 1822-1829.
  5. Research article synthesis and screening of antibacterial and antifungal activity of 6-amino-4-(aryl/heteroaryl) phenyl-3-methyl-2, 4-dihydropyrano [2, 3-c] pyrazole-5-carboxamide derivatives[J].  |  Amin M B N, Parikh A R, Parikh H. 2014,. Sch. Acad. J. Pharm,. 3:: 208-212.
  6. Densely functionalized 1, 2-dihydrobenzo [b][1, 6] naphthyridines: one-pot synthesis via sequential Ugi and Heck reactions[J].  |  Asthana M, Sharma N, Singh R M. 2014,. Tetrahedron,. 70(43):: 7996-8003.
  7. Nitrogen‐Doped TiO2 Nanotubes‐Catalyzed Synthesis of Small D‐π‐A‐Type Knoevenagel Adducts and β‐Enaminones[J].  |  Sultana S, Kumar G, Sarma L S,. 2023. European Journal of Organic Chemistry,., 26(10):: e202300032.
  8. Recent developments on the synthesis of copper and cobalt-Schiff base complexes and their assessment as anti-tuberculosis drugs[J].  |  Malav R, Ray S., 2024: Chemical Papers. 1-24..

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

2-Chloro-6-methylquinoline-3-carboxaldehyde, 5 g

sc-254214
5 g
$93.00