Molecular structure of 20-hydroxy N-Arachidonoyl Taurine
20-hydroxy N-Arachidonoyl Taurine
Application:
20-hydroxy N-Arachidonoyl Taurine is A prominent member of fatty acyl amides of taurine
Molecular Weight:
427.6
Molecular Formula:
C21H35NO5S
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
Arachidonic acid is metabolized by cytochrome P450 (CYP450) 4A ω-hydroxylase to 20-HETE, which acts as a vasoconstrictor in the kidney and brain(1). During mass spectrometry lipidomics analysis of rat brain, a series of fatty acyl amides of taurine was discovered, arachidonoyl taurine is a prominent member(2). 20-hydroxy N-Arachidonoyl taurine is a potential CYP450 metabolite of N-arachidonoyl taurine and can possibly activate members of the transient receptor potential (TRP) family of calcium channels(3).
20-hydroxy N-Arachidonoyl Taurine References
1 McGiff, J.C., Quilley, J. 20-HETE and the kidney: Resolution of old problems and new beginnings. Am J Physiol 277 R607-R623 (1999). 2 Cravatt, B.F., Maxey, K.M. . (2004). 3 Saghatelian, A., McKinney, M.K., Bandell, M., et al. A FAAH-regulated class of N-acyl taurines that activates TRP ion channels. Biochemistry 45(30) 9007-9015 (2006).Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
20-hydroxy N-Arachidonoyl Taurine, 25 µg | sc-220840 | 25 µg | $238.00 | |||
20-hydroxy N-Arachidonoyl Taurine, 50 µg | sc-220840A | 50 µg | $450.00 |