ACPL2 Antibody (H-4): sc-377262
- ACPL2 Antibody (H-4) is a mouse monoclonal IgG1 κ ACPL2 antibody provided at 200 µg/ml
- specific for an epitope mapping between amino acids 37-73 within an internal region of ACPL2 of human origin
- ACPL2 Antibody (H-4) is recommended for detection of ACPL2 of mouse, rat and human origin by WB, IP, IF and ELISA
- Anti-ACPL2 Antibody (H-4) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- m-IgG Fc BP-HRP and m-IgG1 BP-HRP are the preferred secondary detection reagents for ACPL2 Antibody (H-4) for WB applications. These reagents are now offered in bundles with ACPL2 Antibody (H-4) (see ordering information below).
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ACPL2 Antibody (H-4) is a mouse monoclonal IgG1 kappa light chain antibody that detects ACPL2 protein of mouse, rat, and human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). ACPL2 (H-4) antibody is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. ACPL2 protein, also known as acid phosphatase-like 2, UNQ370, or PRO706, is a 480 amino acid secreted protein that catalyzes the hydrolysis of phosphate monoesters into alcohol and inorganic phosphate, a process vital for energy metabolism and signal transduction. ACPL2 is expressed in two alternatively spliced isoforms and is encoded by a gene located on chromosome 3, which harbors over 1,100 genes, including those associated with critical tumor suppressor functions and various genetic diseases. ACPL2′s presence in the extracellular environment suggests involvement in intercellular communication and potential implications in cancer biology, as enzymatic activity may influence tumor progression and metastasis.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
ACPL2 Antibody (H-4) References:
- Molecular cytogenetic dissection of human chromosomes 3 and 21 evolution. | Müller, S., et al. 2000. Proc Natl Acad Sci U S A. 97: 206-11. PMID: 10618396
- [New tumor suppressor genes in hot spots of human chromosome 3: new methods of identification]. | Braga, EA., et al. 2003. Mol Biol (Mosk). 37: 194-211. PMID: 12723467
- Plasticity of human chromosome 3 during primate evolution. | Tsend-Ayush, E., et al. 2004. Genomics. 83: 193-202. PMID: 14706448
- Genomic structure and paralogous regions of the inversion breakpoint occurring between human chromosome 3p12.3 and orangutan chromosome 2. | Yue, Y., et al. 2005. Cytogenet Genome Res. 108: 98-105. PMID: 15545721
- Comparative cytogenetics of human chromosome 3q21.3 reveals a hot spot for ectopic recombination in hominoid evolution. | Yue, Y., et al. 2005. Genomics. 85: 36-47. PMID: 15607420
- Evolutionarily plastic regions at human 3p21.3 coincide with tumor breakpoints identified by the 'elimination test'. | Darai, E., et al. 2005. Genomics. 86: 1-12. PMID: 15913951
- The DNA sequence, annotation and analysis of human chromosome 3. | Muzny, DM., et al. 2006. Nature. 440: 1194-8. PMID: 16641997
- Establishment and characterization of two uveal melanoma cell lines derived from tumors with loss of one chromosome 3. | Nareyeck, G., et al. 2006. Exp Eye Res. 83: 858-64. PMID: 16750193
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
ACPL2 Antibody (H-4) | sc-377262 | 200 µg/ml | $316.00 | |||
ACPL2 Antibody (H-4): m-IgG Fc BP-HRP Bundle | sc-527590 | 200 µg Ab; 10 µg BP | $354.00 | |||
ACPL2 Antibody (H-4): m-IgG1 BP-HRP Bundle | sc-532963 | 200 µg Ab; 20 µg BP | $354.00 | |||
ACPL2 Antibody (H-4) AC | sc-377262 AC | 500 µg/ml, 25% agarose | $416.00 | |||
ACPL2 Antibody (H-4) HRP | sc-377262 HRP | 200 µg/ml | $316.00 | |||
ACPL2 Antibody (H-4) FITC | sc-377262 FITC | 200 µg/ml | $330.00 | |||
ACPL2 Antibody (H-4) PE | sc-377262 PE | 200 µg/ml | $343.00 | |||
ACPL2 Antibody (H-4) Alexa Fluor® 488 | sc-377262 AF488 | 200 µg/ml | $357.00 | |||
ACPL2 Antibody (H-4) Alexa Fluor® 546 | sc-377262 AF546 | 200 µg/ml | $357.00 | |||
ACPL2 Antibody (H-4) Alexa Fluor® 594 | sc-377262 AF594 | 200 µg/ml | $357.00 | |||
ACPL2 Antibody (H-4) Alexa Fluor® 647 | sc-377262 AF647 | 200 µg/ml | $357.00 | |||
ACPL2 Antibody (H-4) Alexa Fluor® 680 | sc-377262 AF680 | 200 µg/ml | $357.00 | |||
ACPL2 Antibody (H-4) Alexa Fluor® 790 | sc-377262 AF790 | 200 µg/ml | $357.00 | |||
ACPL2 (H-4) Neutralizing Peptide | sc-377262 P | 100 µg/0.5 ml | $68.00 |