ASCL1 Antibody (G-9): sc-374550
- ASCL1 Antibody (G-9) is a mouse monoclonal IgG1 κ, cited in 3 publications, provided at 200 µg/ml
- raised against amino acids 181-236 mapping at the C-terminus of ASCL1 of human origin
- recommended for detection of ASCL1 of mouse, rat and human origin by WB, IP, IF and ELISA; also reactive with additional species, including canine
- TransCruz reagent for ChIP application (sc-374550 X, 200 µg/0.1 ml)
- m-IgG Fc BP-HRP and m-IgG1 BP-HRP are the preferred secondary detection reagents for ASCL1 Antibody (G-9) for WB applications. These reagents are now offered in bundles with ASCL1 Antibody (G-9) (see ordering information below).
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ASCL1 Antibody (G-9) is a mouse monoclonal IgG1 antibody that detects ASCL1 in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). ASCL1, also known as ASH1, is a basic helix-loop-helix transcription factor that plays a crucial role in the early development of the nervous system, particularly in the formation and survival of autonomic neurons. ASCL1 is predominantly expressed in the fetal brain, where ASCL1 is essential for the proper development of neuronal circuits within the central nervous system. Notably, ASCL1 interacts with the transcription factor MEF-2A, which may influence the expression of genes critical for neuronal differentiation and circuit formation. The significance of ASCL1 extends beyond development, as high expression levels in neuroendocrine tumors, including medullary thyroid cancer and small cell lung cancer, suggest ASCL1′s potential as a biomarker for cancers exhibiting neuroendocrine features. Additionally, the ASCL1 gene, located on human chromosome 12, contains a trinucleotide repeat region, positioning ASCL1 as a candidate locus for inherited diseases. anti-ASCL1 antibody (G-9) is an invaluable tool for researchers investigating ASCL1′s roles in both developmental biology and cancer research.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
ASCL1 Antibody (G-9) | sc-374550 | 200 µg/ml | $316.00 | |||
ASCL1 Antibody (G-9): m-IgG Fc BP-HRP Bundle | sc-540472 | 200 µg Ab; 10 µg BP | $354.00 | |||
ASCL1 Antibody (G-9): m-IgG1 BP-HRP Bundle | sc-542145 | 200 µg Ab; 20 µg BP | $354.00 | |||
ASCL1 Antibody (G-9) X | sc-374550 X | 200 µg/0.1 ml | $316.00 |