CD14 Antibody (5A3B11B5): sc-58951
- CD14 Antibody (5A3B11B5) is a mouse monoclonal IgG2b κ CD14 antibody, cited in 26 publications, provided at 200 µg/ml
- raised against recombinant CD14 of human origin
- CD14 Antibody (5A3B11B5) is recommended for detection of CD14 of human origin by WB, IP, IF and IHC(P)
- Anti-CD14 Antibody (5A3B11B5) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- m-IgG Fc BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for CD14 Antibody (5A3B11B5) for WB and IHC(P) applications. These reagents are now offered in bundles with CD14 Antibody (5A3B11B5) (see ordering information below).
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CD14 Antibody (5A3B11B5) is a mouse monoclonal IgG2b kappa light chain antibody raised against recombinant CD14 of human origin, recommended for the detection of CD14 by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and immunohistochemistry with paraffin-embedded sections (IHCP). CD14, also known as the monocyte differentiation antigen CD14 or myeloid cell-specific leucine-rich glycoprotein, is a glycosylphosphatidylinositol (GPI)-anchored membrane glycoprotein predominantly expressed on the surface of monocytes, macrophages, and neutrophils. Post-translational modifications of CD14, including N-linked glycosylation and the addition of the GPI anchor, are crucial for proper localization to the cell membrane and function in the immune response. The glycosylation of CD14 affects binding to lipopolysaccharide (LPS) and other pathogen-associated molecular patterns (PAMPs), facilitating the activation of innate immune signaling pathways. These modifications enhance CD14′s affinity for ligands and interaction with co-receptors such as Toll-like receptor 4 (TLR4) and myeloid differentiation factor 2 (MD-2), which are essential for initiating inflammatory responses to bacterial infections. Anti-CD14 antibody (5A3B11B5) serves as a valuable tool for researchers studying immune recognition, signal transduction, and the role of post-translational modifications in protein function.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
CD14 Antibody (5A3B11B5) | sc-58951 | 200 µg/ml | $316.00 | |||
CD14 Antibody (5A3B11B5): m-IgG Fc BP-HRP Bundle | sc-528632 | 200 µg Ab; 10 µg BP | $354.00 | |||
CD14 Antibody (5A3B11B5): m-IgGκ BP-HRP Bundle | sc-521062 | 200 µg Ab, 40 µg BP | $354.00 | |||
CD14 Antibody (5A3B11B5) AC | sc-58951 AC | 500 µg/ml, 25% agarose | $416.00 | |||
CD14 Antibody (5A3B11B5) HRP | sc-58951 HRP | 200 µg/ml | $316.00 | |||
CD14 Antibody (5A3B11B5) FITC | sc-58951 FITC | 200 µg/ml | $330.00 | |||
CD14 Antibody (5A3B11B5) PE | sc-58951 PE | 200 µg/ml | $343.00 | |||
CD14 Antibody (5A3B11B5) Alexa Fluor® 488 | sc-58951 AF488 | 200 µg/ml | $357.00 | |||
CD14 Antibody (5A3B11B5) Alexa Fluor® 546 | sc-58951 AF546 | 200 µg/ml | $357.00 | |||
CD14 Antibody (5A3B11B5) Alexa Fluor® 594 | sc-58951 AF594 | 200 µg/ml | $357.00 | |||
CD14 Antibody (5A3B11B5) Alexa Fluor® 647 | sc-58951 AF647 | 200 µg/ml | $357.00 | |||
CD14 Antibody (5A3B11B5) Alexa Fluor® 680 | sc-58951 AF680 | 200 µg/ml | $357.00 | |||
CD14 Antibody (5A3B11B5) Alexa Fluor® 790 | sc-58951 AF790 | 200 µg/ml | $357.00 |