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eHAND Antibody (E-10) is a mouse monoclonal IgG1 antibody that detects eHAND in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). eHAND, also known as HAND1, HXT, or Thing1, is a crucial member of the basic-helix-loop-helix transcription factor family, playing a significant role in cardiac development and left-right asymmetry of the heart. eHAND is predominantly expressed on the left side of the developing heart tube and in the systemic ventricle, where eHAND is essential for the proper formation of heart chambers during cardiogenesis. eHAND′s structure, characterized by its basic helix-loop-helix motif, allows DNA binding and regulation of target genes involved in cardiac morphogenesis. Understanding eHAND′s structural features is vital, as mutations or dysregulation can lead to congenital heart defects, highlighting eHAND′s importance in both developmental biology and potential clinical applications. anti-eHAND antibody (E-10) is an invaluable tool for researchers studying cardiac development and related pathologies, providing insights into the molecular mechanisms underlying heart formation and function.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
eHAND Antibody (E-10) | sc-374296 | 200 µg/ml | $316.00 | |||
eHAND Antibody (E-10): m-IgG Fc BP-HRP Bundle | sc-540431 | 200 µg Ab; 10 µg BP | $354.00 | |||
eHAND Antibody (E-10): m-IgG1 BP-HRP Bundle | sc-542117 | 200 µg Ab; 20 µg BP | $354.00 | |||
eHAND Antibody (E-10) X | sc-374296 X | 200 µg/0.1 ml | $316.00 | |||
eHAND (E-10) Neutralizing Peptide | sc-374296 P | 100 µg/0.5 ml | $68.00 |