Glucose Transporter Glut3 Antibody (G-5): sc-74399

Glut3 Antibody (G-5) is a mouse monoclonal IgG1 kappa light chain antibody that detects Glut3 protein of mouse, rat, and human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). anti-Glut3 antibody (G-5) is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. Glut3, also known as SLC2A3, plays a critical role in glucose transport, particularly in the brain, where Glut3 is predominantly expressed. This high-affinity glucose transporter is essential for maintaining glucose homeostasis in neuronal tissues, as neurons rely heavily on glucose as their primary energy source. Glut3′s ability to facilitate rapid glucose uptake is vital for supporting the high metabolic demands of the brain, especially during periods of increased activity or stress. Understanding Glut3 function is crucial, as dysregulation of glucose transport can lead to various neurological disorders and metabolic diseases. Using Glut3 (G-5) antibody in research can provide valuable insights into glucose transport mechanisms and their implications in health and disease.

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Glucose Transporter Glut3 Antibody (G-5) References:

1. Differential localization of glucose transporter isoforms in non-polarized mammalian cells: distribution of GLUT1 but not GLUT3 to detergent-resistant membrane domains.  |  Sakyo, T. and Kitagawa, T. 2002. Biochim Biophys Acta. 1567: 165-75. PMID: 12488050
2. Distinct regulation of glucose transport and GLUT1/GLUT3 transporters by glucose deprivation and IGF-I in chromaffin cells.  |  Fladeby, C., et al. 2003. Biochim Biophys Acta. 1593: 201-8. PMID: 12581864
3. Glucose uptake in PC12 cells: GLUT3 vesicle trafficking and fusion as revealed with a novel GLUT3-GFP fusion protein.  |  Heather West Greenlee, M., et al. 2003. J Neurosci Res. 73: 518-25. PMID: 12898536
4. Inhibition of mitochondrial respiration by nitric oxide rapidly stimulates cytoprotective GLUT3-mediated glucose uptake through 5'-AMP-activated protein kinase.  |  Cidad, P., et al. 2004. Biochem J. 384: 629-36. PMID: 15320870
5. Molecular regulation of GLUT-4 targeting in 3T3-L1 adipocytes.  |  Marsh, BJ., et al. 1995. J Cell Biol. 130: 1081-91. PMID: 7544796
6. Regulation of glucose transporters in cultured rat adipocytes: synergistic effect of insulin and dexamethasone on GLUT4 gene expression through promoter activation.  |  Hajduch, E., et al. 1995. Endocrinology. 136: 4782-9. PMID: 7588207
7. Progressive hippocampal loss of immunoreactive GLUT3, the neuron-specific glucose transporter, after global forebrain ischemia in the rat.  |  McCall, AL., et al. 1995. Brain Res. 670: 29-38. PMID: 7719721
8. Expression and compartmentalization of caveolin in adipose cells: coordinate regulation with and structural segregation from GLUT4.  |  Kandror, KV., et al. 1995. J Cell Biol. 129: 999-1006. PMID: 7744970
9. Hypothalamic GLUT 4 expression: a glucose- and insulin-sensing mechanism?  |  Livingstone, C., et al. 1995. Mol Cell Endocrinol. 107: 67-70. PMID: 7796936
10. Facilitative glucose transporters.  |  Mueckler, M. 1994. Eur J Biochem. 219: 713-25. PMID: 8112322
11. Glucose transporters in the regulation of intestinal, renal, and liver glucose fluxes.  |  Thorens, B. 1996. Am J Physiol. 270: G541-53. PMID: 8928783

Monoclonal antibodies for mammalian and non-mammalian protein targets represent essentially all targets covered by polyclonal antibodies. Over 8,300 of our antibodies are offered as ImmunoCruz^® conjugates which eliminates the need for a secondary antibody.

Santa Cruz Biotechnology antibodies have over 360,000 research citations. Anti-Glucose Transporter Glut3 Antibody (G-5) has 42 citations in a variety of scientific publications.

Primary antibodies like Anti-Glucose Transporter Glut3 Antibody (G-5) for mammalian target proteins are recommended for the detection of a range of mammalian species, primarily of mouse, rat and human species. Many mammalian antibodies are also ideal for veterinary research and reactive with ovine, porcine, caprine, feline, canine, bovine and equine protein targets. Santa Cruz Biotechnology primary monoclonal antibodies are suitable for laboratory research applications and are not intended for diagnostic or therapeutic use.

Glucose Transporter Glut3 Antibody (G-5) Specifications

Alternate Product Name: Glut3

Product Clone Name: G-5

Classification: Primary Antibody

Clonality: Monoclonal Antibody

Antibody Isotype: IgG₁ kappa light chain

Amino Acids: 216-265

Epitope Target: Glut3

Epitope Species: human

Product Reactivity/Detection: Glut3

Species Reactivity/Detection: mouse, rat, human

Additional Mammalian Reactivity: N/A

Additional Non-Mammalian Reactivity: N/A

Applications: WB, IP, IF, ELISA

Vialing Information: Each vial contains 200 µg IgG₁ kappa light chain in 1.0 ml of PBS with < 0.1% sodium azide and 0.1% gelatin

Research Citations: 42 citations in various scientific publications

Available Conjugates/Forms for Glucose Transporter Glut3 Antibody (G-5): AC: Agarose, AF488: Alexa Fluor^® 488, AF546: Alexa Fluor^® 546, AF594: Alexa Fluor^® 594, AF647: Alexa Fluor^® 647, AF680: Alexa Fluor^® 680, AF790: Alexa Fluor^® 790, FITC: Fluoroscein, HRP: Horseradish Peroxidase, PE: Phycoerythrin

The preferred Glucose Transporter Glut3 antibody is Glucose Transporter Glut3 Antibody (B-6): sc-74497.