GSTM2 Antibody (E-9): sc-376486
- GSTM2 Antibody (E-9) is a mouse monoclonal IgG1 κ GSTM2 antibody, cited in 4 publications, provided at 200 µg/ml
- raised against amino acids 1-218 representing full length GSTM2 of human origin
- GSTM2 Antibody (E-9) is recommended for detection of GSTM2 of human origin by WB, IP, IF and ELISA; may cross-react with GSTM1, GSTM3, GSTM4 and GSTM5
- Anti-GSTM2 Antibody (E-9) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- m-IgGκ BP-HRP is the preferred secondary detection reagent for GSTM2 Antibody (E-9) for WB applications. This reagent is now offered in a bundle with GSTM2 Antibody (E-9) (see ordering information below). For additional m-IgGκ BP conjugates see our complete list of Mouse IgG Binding Proteins.
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GSTM2 Antibody (E-9) is a mouse monoclonal IgG1 kappa light chain antibody that detects GSTM2 protein of human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). Anti-GSTM2 antibody (E-9) is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates, providing versatility for different experimental needs. GSTM2 plays a crucial role in detoxification processes, specifically by conjugating with glutathione to neutralize harmful compounds, including carcinogens and environmental toxins. GSTM2 (E-9) antibody helps study cellular protection against oxidative stress and damage, which can lead to various diseases, including cancer. GSTM family, which includes several classes such as mu, pi, and theta, is essential for maintaining cellular homeostasis and responding to toxic insults. Understanding GSTM2′s role in these processes can provide insights into potential biomarkers for disease and targets for therapeutic intervention.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
GSTM2 Antibody (E-9) References:
- Mechanisms of aflatoxin B1 lung tumorigenesis. | Massey, TE., et al. 2000. Exp Lung Res. 26: 673-83. PMID: 11195464
- Multiple isoforms of mitochondrial glutathione S-transferases and their differential induction under oxidative stress. | Raza, H., et al. 2002. Biochem J. 366: 45-55. PMID: 12020353
- Regulation of the gene encoding glutathione S-transferase M1 (GSTM1) by the Myb oncoprotein. | Bartley, PA., et al. 2003. Oncogene. 22: 7570-5. PMID: 14576818
- GSTM1 and APE1 genotypes affect arsenic-induced oxidative stress: a repeated measures study. | Breton, CV., et al. 2007. Environ Health. 6: 39. PMID: 18053222
- Glutathione S-transferase GSTT1 and GSTM1 allozymes: beyond null alleles. | Agúndez, JA. and Ladero, JM. 2008. Pharmacogenomics. 9: 359-63. PMID: 18303971
- Effects of N-acetyltransferase 2 (NAT2), CYP2E1 and Glutathione-S-transferase (GST) genotypes on the serum concentrations of isoniazid and metabolites in tuberculosis patients. | Fukino, K., et al. 2008. J Toxicol Sci. 33: 187-95. PMID: 18544910
- Expressions of glutathione S-transferase alpha, mu, and pi in brains of medically intractable epileptic patients. | Shang, W., et al. 2008. BMC Neurosci. 9: 67. PMID: 18644106
- Glutathione S-transferase m1 and t1 null genotypes increase susceptibility to idiosyncratic drug-induced liver injury. | Lucena, MI., et al. 2008. Hepatology. 48: 588-96. PMID: 18666253
- Increased levels of glutathione S transferases and appearance of novel alpha class isoenzymes in kidneys of mice exposed to mercuric chloride. I. Biochemical and immunohistochemical studies. | McGuire, S., et al. 1997. Nephron. 77: 452-60. PMID: 9434069
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
GSTM2 Antibody (E-9) | sc-376486 | 200 µg/ml | $316.00 | |||
GSTM2 Antibody (E-9): m-IgGκ BP-HRP Bundle | sc-522971 | 200 µg Ab, 40 µg BP | $354.00 | |||
GSTM2 Antibody (E-9) AC | sc-376486 AC | 500 µg/ml, 25% agarose | $416.00 | |||
GSTM2 Antibody (E-9) HRP | sc-376486 HRP | 200 µg/ml | $316.00 | |||
GSTM2 Antibody (E-9) FITC | sc-376486 FITC | 200 µg/ml | $330.00 | |||
GSTM2 Antibody (E-9) PE | sc-376486 PE | 200 µg/ml | $343.00 | |||
GSTM2 Antibody (E-9) Alexa Fluor® 488 | sc-376486 AF488 | 200 µg/ml | $357.00 | |||
GSTM2 Antibody (E-9) Alexa Fluor® 546 | sc-376486 AF546 | 200 µg/ml | $357.00 | |||
GSTM2 Antibody (E-9) Alexa Fluor® 594 | sc-376486 AF594 | 200 µg/ml | $357.00 | |||
GSTM2 Antibody (E-9) Alexa Fluor® 647 | sc-376486 AF647 | 200 µg/ml | $357.00 | |||
GSTM2 Antibody (E-9) Alexa Fluor® 680 | sc-376486 AF680 | 200 µg/ml | $357.00 | |||
GSTM2 Antibody (E-9) Alexa Fluor® 790 | sc-376486 AF790 | 200 µg/ml | $357.00 |