HSC70/HSP70 Antibody (5A5): sc-59571
- HSC70/HSP70 Antibody (5A5) is a mouse monoclonal IgG2b κ, cited in 4 publications, provided at 200 µg/ml
- raised against recombinant HSP 70/HSC 70 of human origin
- recommended for detection of several members of the HSP 70 gene family including HSP 70, HSC 70, GRP 78 and, following heat shock, HSP 72 of mouse, rat, human and Drosophila origin by WB, IP, IF and IHC(P)
- See HSC70/HSP70 (W27): sc-24 for HSC70/HSP70 antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
- m-IgG Fc BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for HSC70/HSP70 Antibody (5A5) for WB and IHC(P) applications. These reagents are now offered in bundles with HSC70/HSP70 Antibody (5A5) (see ordering information below).
HSP 70/HSC 70 Antibody (5A5) is a mouse monoclonal IgG2b antibody that detects HSP 70/HSC 70 in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and immunohistochemistry. HSP 70/HSC 70 are crucial members of the heat shock protein family, functioning primarily as molecular chaperones that assist in proper folding of nascent polypeptide chains and assembly of multi-protein complexes. HSP 70/HSC 70′s ability to prevent misfolded protein accumulation is vital for cellular homeostasis, particularly under stress conditions such as heat shock, where HSP 70 expression significantly increases. HSP 70/HSC 70 are predominantly located in cytosol and nucleus of mammalian cells, playing essential roles in cytosolic endoplasmic reticulum and mitochondrial import machinery. HSP 70/HSC 70 interaction with various client proteins highlights their importance in maintaining protein quality control and cellular function. ATPase activity of these chaperones provides energy necessary for conformational changes during folding processes. Anti-HSP 70/HSC 70 antibody (5A5) serves as an invaluable tool for researchers studying protein folding, stress responses, and cellular proteostasis mechanisms.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
HSC70/HSP70 Antibody (5A5) | sc-59571 | 200 µg/ml | $322.00 | |||
HSC70/HSP70 Antibody (5A5): m-IgG Fc BP-HRP Bundle | sc-537162 | 200 µg Ab; 10 µg BP | $361.00 | |||
HSC70/HSP70 Antibody (5A5): m-IgGκ BP-HRP Bundle | sc-534359 | 200 µg Ab; 40 µg BP | $361.00 |