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L-Proline 4-nitroanilide (CAS 7369-91-7)

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Alternate Names:
L-Proline 4-nitroanilide hydrobromide
CAS Number:
7369-91-7
Molecular Weight:
316.15
Molecular Formula:
C11H13N3O3•HBr
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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L-Proline 4-nitroanilide functions as a substrate for the enzyme proline iminopeptidase. This enzyme catalyzes the hydrolysis of L-proline 4-nitroanilide to release L-proline and 4-nitroaniline. The mechanism of action involves the binding of the substrate to the active site of the enzyme, leading to the cleavage of the amide bond between L-proline and 4-nitroanilide.


L-Proline 4-nitroanilide (CAS 7369-91-7) References

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  5. The structure of Mlc titration factor A (MtfA/YeeI) reveals a prototypical zinc metallopeptidase related to anthrax lethal factor.  |  Xu, Q., et al. 2012. J Bacteriol. 194: 2987-99. PMID: 22467785
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  12. Synthesis of a chromogenic proline-containing glycopeptide  |  Steffan, W., Schutkowski, M., & Fischer, G. 1996. Chemical Communications. (3): 313-314.
  13. Direct asymmetric aldol reactions catalyzed by l-proline-2, 4, 6-trinitroanilide  |  Sato, K., Kuriyama, M., Shimazawa, R., Morimoto, T., Kakiuchi, K., & Shirai, R. 2008. Tetrahedron Letters. 49(15): 2402-2406.

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

L-Proline 4-nitroanilide, 1 g

sc-300893
1 g
$150.00

L-Proline 4-nitroanilide, 5 g

sc-300893A
5 g
$565.00