Molecular structure of Phentolamine mesylate, CAS Number: 65-28-1
Phentolamine mesylate (CAS 65-28-1)
See product citations (2)
Alternate Names:
Phentolamine Methanesulfonate Salt; 2-[N-(m-Hydroxyphenyl)-p-toluidinomethyl]imidazoline; Methanesulfonate
Application:
Phentolamine mesylate is an α-adrenergic blocker
CAS Number:
65-28-1
Purity:
≥99%
Molecular Weight:
377.46
Molecular Formula:
C17H19N3O•CH3SO3H
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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Phentolamine mesylate acts as an alpha-AR (alpha-Adrenergic) blocker. Phentolamine mesylate, a synthetic compound derived from the alkaloid phentolamine naturally occurring in Rauwolfia serpentina roots, exhibits antimuscarinic properties. This substance has found utility in in vitro investigations, specifically exploring the impact of alpha-adrenergic receptor antagonists on diverse cell types.
Phentolamine mesylate (CAS 65-28-1) References
- Oral phentolamine: an alpha-1, alpha-2 adrenergic antagonist for the treatment of erectile dysfunction. | Goldstein, I. 2000. Int J Impot Res. 12 Suppl 1: S75-80. PMID: 10845768
- Phentolamine mesylate relaxes rabbit corpus cavernosum by a nonadrenergic, noncholinergic mechanism. | Vemulapalli, S. and Kurowski, S. 2001. Fundam Clin Pharmacol. 15: 1-7. PMID: 11468007
- Vasoactive intestinal polypeptide/phentolamine for intracavernosal injection in erectile dysfunction. | Dinsmore, WW. and Wyllie, MG. 2008. BJU Int. 102: 933-7. PMID: 18485029
- Phentolamine mesylate for accelerating recovery from lip and tongue anesthesia. | Hersh, EV. and Lindemeyer, RG. 2010. Dent Clin North Am. 54: 631-42. PMID: 20831927
- Stability of papaverine hydrochloride and phentolamine mesylate in injectable mixtures. | Tu, YH., et al. 1987. Am J Hosp Pharm. 44: 2524-7. PMID: 2446497
- Phentolamine mesylate: It's role as a reversal agent for unwarranted prolonged local analgesia. | Grover, HS., et al. 2015. J Indian Soc Pedod Prev Dent. 33: 265-8. PMID: 26381625
- Phentolamine mesylate to reverse oral soft-tissue local anesthesia: A systematic review and meta-analysis. | Prados-Frutos, JC., et al. 2015. J Am Dent Assoc. 146: 751-9.e3. PMID: 26409985
- Effectiveness and safety of phentolamine mesylate in routine dental care. | Daubländer, M., et al. 2017. J Am Dent Assoc. 148: 149-156. PMID: 28126226
- Phentolamine Mesylate May be a Safe and Effective Option to Reduce Discomfort and Time to Recovery After Dental Care With Local Anesthesia. | Helmi, M., et al. 2018. J Evid Based Dent Pract. 18: 181-184. PMID: 29747805
- Safety profile of phentolamine mesylate as reversal agent of pulpal and soft tissue dental anesthesia: a systematic review and meta-analysis. | Vinnakota, DN. and Kamatham, R. 2019. Quintessence Int. 50: 568-575. PMID: 31134227
- Phentolamine mesylate: pharmacology, efficacy, and safety. | Hersh, EV., et al. 2019. Gen Dent. 67: 12-17. PMID: 31199738
- Effect of phentolamine mesylate on regression of lidocaine-epinephrine epidural anaesthesia in sheep. | Imani Rastabi, H., et al. 2020. Vet Anaesth Analg. 47: 267-273. PMID: 32007444
- Diagnosis and therapy of erectile dysfunction using papaverine and phentolamine. | Zentgraf, M., et al. 1988. Urol Int. 43: 65-75. PMID: 3291360
- Phentolamine mesylate relaxes penile corpus cavernosum tissue by adrenergic and non-adrenergic mechanisms. | Traish, A., et al. 1998. Int J Impot Res. 10: 215-23. PMID: 9884917
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AR.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Phentolamine mesylate, 50 mg | sc-205803 | 50 mg | $73.00 | |||
Phentolamine mesylate, 100 mg | sc-205803A | 100 mg | $138.00 |