plexin-A3 Antibody (A-8): sc-374662
- plexin-A3 Antibody (A-8) is a mouse monoclonal IgG1 κ plexin-A3 antibody, cited in 1 publications, provided at 200 µg/ml
- raised against amino acids 961-1050 of plexin-A3 of human origin
- plexin-A3 Antibody (A-8) is recommended for detection of plexin-A3 of human origin by WB, IP, IF, IHC(P) and ELISA
- Anti-plexin-A3 Antibody (A-8) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- m-IgG Fc BP-HRP is the preferred secondary detection reagent for plexin-A3 Antibody (A-8) for WB and IHC(P) applications. This reagent is now offered in a bundle with plexin-A3 Antibody (A-8) (see ordering information below).
plexin-A3 Antibody (A-8) is a mouse monoclonal IgG1 kappa light chain antibody that detects plexin-A3 protein of human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), and enzyme-linked immunosorbent assay (ELISA). anti-plexin-A3 antibody (A-8) is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. Plexin-A3 plays a crucial role in mediating cell-repelling cues, which are essential for proper neuronal development and guidance. This function is particularly important in neural circuitry, where precise positioning of neurons is vital for establishing functional connections. plexin-A3 (A-8) antibody interaction with semaphorins, a family of proteins involved in axon guidance, underscores its significance in both developmental and pathological processes, including cancer metastasis and neurodegenerative diseases. plexin-A3 monoclonal antibody (A-8) enables researchers to gain valuable insights into cell signaling mechanisms and plexin roles in various biological contexts.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
plexin-A3 Antibody (A-8) References:
- Plexin-neuropilin-1 complexes form functional semaphorin-3A receptors. | Takahashi, T., et al. 1999. Cell. 99: 59-69. PMID: 10520994
- Plexins are a large family of receptors for transmembrane, secreted, and GPI-anchored semaphorins in vertebrates. | Tamagnone, L., et al. 1999. Cell. 99: 71-80. PMID: 10520995
- Plexins, semaphorins, and scatter factor receptors: a common root for cell guidance signals? | Artigiani, S., et al. 1999. IUBMB Life. 48: 477-82. PMID: 10637762
- The semaphorin genes encode a family of transmembrane and secreted growth cone guidance molecules. | Kolodkin, AL., et al. 1993. Cell. 75: 1389-99. PMID: 8269517
- Identification of plexin family molecules in mice. | Kameyama, T., et al. 1996. Biochem Biophys Res Commun. 226: 396-402. PMID: 8806646
- Control of invasive growth by hepatocyte growth factor (HGF) and related scatter factors. | Tamagnone, L. and Comoglio, PM. 1997. Cytokine Growth Factor Rev. 8: 129-42. PMID: 9244408
- Plexin A is a neuronal semaphorin receptor that controls axon guidance. | Winberg, ML., et al. 1998. Cell. 95: 903-16. PMID: 9875845
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
plexin-A3 Antibody (A-8) | sc-374662 | 200 µg/ml | $316.00 | |||
plexin-A3 Antibody (A-8): m-IgG Fc BP-HRP Bundle | sc-525984 | 200 µg Ab; 10 µg BP | $354.00 | |||
plexin-A3 Antibody (A-8) AC | sc-374662 AC | 500 µg/ml, 25% agarose | $416.00 | |||
plexin-A3 Antibody (A-8) HRP | sc-374662 HRP | 200 µg/ml | $316.00 | |||
plexin-A3 Antibody (A-8) FITC | sc-374662 FITC | 200 µg/ml | $330.00 | |||
plexin-A3 Antibody (A-8) PE | sc-374662 PE | 200 µg/ml | $343.00 | |||
plexin-A3 Antibody (A-8) Alexa Fluor® 488 | sc-374662 AF488 | 200 µg/ml | $357.00 | |||
plexin-A3 Antibody (A-8) Alexa Fluor® 546 | sc-374662 AF546 | 200 µg/ml | $357.00 | |||
plexin-A3 Antibody (A-8) Alexa Fluor® 594 | sc-374662 AF594 | 200 µg/ml | $357.00 | |||
plexin-A3 Antibody (A-8) Alexa Fluor® 647 | sc-374662 AF647 | 200 µg/ml | $357.00 | |||
plexin-A3 Antibody (A-8) Alexa Fluor® 680 | sc-374662 AF680 | 200 µg/ml | $357.00 | |||
plexin-A3 Antibody (A-8) Alexa Fluor® 790 | sc-374662 AF790 | 200 µg/ml | $357.00 |