(S)-6-Methoxy-2,5,7,8-tetramethylchromane-2-carboxylic acid (CAS 135806-59-6)
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A chiral derivatizing agent for alcohols. Some methyl substituted primary alcohols which are typically difficult to separate otherwise, can also be separated. (S)-6-Methoxy-2,5,7,8-tetramethylchromane-2-carboxylic acid, is an analog of vitamin E that readily dissolves in water. It finds utility in capillary gas chromatography (GC) and supercritical fluid chromatography (SFC) for the analysis of chiral alcohols. This derivative aids in the separation and identification of their enantiomers. When it comes to the enantiomeric separation of several benzodiazepines, (S)-Trolox methyl ether plays a role. It facilitates their analysis using gas chromatography (GC), supercritical fluid chromatography (SFC), and subcritical fluid chromatography techniques.
(S)-6-Methoxy-2,5,7,8-tetramethylchromane-2-carboxylic acid (CAS 135806-59-6) References
- Enzymatic Preparation of (R)-3-Hydroxy-2-Methylpropyl Butyrate by Asymmetric Hydrolysis | Beat Wirz, Rudolf Schmid & Willy Walther. 1990. Biocatalysis. 3: 159-167.
- (S) -TroloxTM methyl ether, a powerful derivatizing reagent for the determination of the enantiomeric purity of chiral alcohols by GC and SFC with achiral columns | Wiley Walther, Walter Vetter, Thomas Netscher. 1992. Journal of Microcolumn. 4: 45-49.
- Direct and indirect approaches to enantiomeric separation of benzodiazepines using micro column techniques | Susanne R. Almquist a, Patrik Petersson a, Willi Walther b, Karin E. Markides a. 1994. Journal of Chromatography A. 679: 139-146.
- Design and development of chiral reagents for the chromatographic e.e. determination of chiral alcohols | Willi Walther, Thomas Netscher. 1996. Chirality. 8: 397-401.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
(S)-6-Methoxy-2,5,7,8-tetramethylchromane-2-carboxylic acid, 50 mg | sc-253526 | 50 mg | $133.00 |