Date published: 2026-4-3

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Tiliroside (CAS 20316-62-5)

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Application:
Tiliroside is an antioxidant, antiproliferating, and free radical scavenger agent
CAS Number:
20316-62-5
Purity:
≥97%
Molecular Weight:
594.52
Molecular Formula:
C30H26O13
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Tiliroside, a flavanoid originally extracted from Magnoliafargesii, has been shown to have potent anti-complement activity on the classical pathway of the complement system. Additionally, this compound has been reported to have significant anti-proliferative effects. Furthermore, Tiliroside has been noted to strongly suppress serum GPT and GOT elevations in D-galactosamine (D-GaIN)/Lipopolysaccharide (sc-221854)(LPS)-induced liver injury in mice via inhibition of TNF-α production. Additionally, Tiliroside demonstrates antioxidant, anti-inflammatory, and scavenger properties through inhibition of enzymatic and non-enzymatic lipid peroxidation.


Tiliroside (CAS 20316-62-5) References

  1. Cytotoxic and antiproliferative effects of heptaacetyltiliroside on human leukemic cell lines.  |  Dimas, K., et al. 1999. Leuk Res. 23: 1021-33. PMID: 10576507
  2. Hepatoprotective principles from the flowers of Tilia argentea (linden): structure requirements of tiliroside and mechanisms of action.  |  Matsuda, H., et al. 2002. Bioorg Med Chem. 10: 707-12. PMID: 11814859
  3. Assessment of the anti-inflammatory activity and free radical scavenger activity of tiliroside.  |  Sala, A., et al. 2003. Eur J Pharmacol. 461: 53-61. PMID: 12568916
  4. Flavonoids from the leaves of Litsea japonica and their anti-complement activity.  |  Lee, SY., et al. 2005. Phytother Res. 19: 273-6. PMID: 16041765
  5. Tiliroside and gnaphaliin inhibit human low density lipoprotein oxidation.  |  Schinella, GR., et al. 2007. Fitoterapia. 78: 1-6. PMID: 17084992
  6. Tiliroside disrupted iron homeostasis and induced ferroptosis via directly targeting calpain-2 in pancreatic cancer cells.  |  Xu, M., et al. 2024. Phytomedicine. 127: 155392. PMID: 38412575
  7. Identification of α-Glucosidase-Inhibitors in Edgeworthia gardneri (Wall.) Meisn. Using UPLC-Q-TOF-MS/MS Analysis.  |  Li, L., et al. 2024. Plant Foods Hum Nutr. 79: 381-386. PMID: 38436827
  8. Chemical Constituents, Hypolipidemic, and Hypoglycemic Activities of Edgeworthia gardneri Flowers.  |  Zhang, X., et al. 2024. Plant Foods Hum Nutr. 79: 440-450. PMID: 38441843
  9. Antiplatelet and Anticoagulant Effects of Two New Phenylpropanoid Sucrose Esters and Other Secondary Metabolites from the Aerial Part of Canna edulis.  |  Nguyen, TVA., et al. 2024. Chem Biodivers. 21: e202400302. PMID: 38454878
  10. Probiotic-fermented tomato with hepatic lipid metabolism modulation effects: analysis of physicochemical properties, bioactivities, and potential bioactive compounds.  |  Wei, B., et al. 2024. Food Funct. 15: 4874-4886. PMID: 38590277
  11. Production of Polyphenolic Natural Products by Bract-Derived Tissue Cultures of Three Medicinal Tilia spp.: A Comparative Untargeted Metabolomics Study.  |  Szűcs, Z., et al. 2024. Plants (Basel). 13: PMID: 38794359
  12. Research on the pharmacognostic characteristics, physicochemical properties and in vitro antioxidant potency of Rosa laxa Retz. flos.  |  Guo, Y., et al. 2024. Microsc Res Tech.. PMID: 38856633
  13. Anti-complement activity of tiliroside from the flower buds of Magnolia fargesii.  |  Jung, KY., et al. 1998. Biol Pharm Bull. 21: 1077-8. PMID: 9821813

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Tiliroside, 1 mg

sc-202364
1 mg
$175.00

Tiliroside, 5 mg

sc-202364A
5 mg
$750.00