ODC Inhibitors
Items 1 to 10 of 13 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Caffeic acid phenethyl ester | 104594-70-9 | sc-200800 sc-200800A sc-200800B | 20 mg 100 mg 1 g | $71.00 $296.00 $612.00 | 19 | |
Caffeic acid phenethyl ester is a notable compound characterized by its ability to engage in diverse molecular interactions due to its phenolic structure. As an acid halide, it showcases unique reactivity patterns, particularly in esterification and acyl transfer reactions. The presence of the phenethyl moiety enhances its electrophilic character, promoting selective nucleophilic attacks. Additionally, its hydrophobic regions influence solubility and reactivity in organic solvents, making it a versatile participant in synthetic chemistry. | ||||||
Caffeic acid methyl ester | 3843-74-1 | sc-204664 | 50 mg | $50.00 | 1 | |
Caffeic acid methyl ester exhibits intriguing reactivity as an acid halide, primarily due to its ester functional group, which facilitates acylation reactions. Its unique structure allows for specific interactions with nucleophiles, leading to selective substitution pathways. The compound's hydrophilic and hydrophobic balance influences its solubility profile, enhancing its role in various organic transformations. Furthermore, its kinetic behavior in reactions can be modulated by solvent polarity, making it a valuable component in synthetic methodologies. | ||||||
Difluoromethylornithine | 70052-12-9 | sc-204723 sc-204723A sc-204723B sc-204723C sc-204723D sc-204723E | 10 mg 25 mg 100 mg 250 mg 1 g 5 g | $59.00 $133.00 $161.00 $317.00 $983.00 $4821.00 | 2 | |
DFMO is a well-known and potent irreversible inhibitor of ODC. It has been extensively studied as an anti-cancer drug and is used in research for various malignancies. | ||||||
DL-α-Difluoromethylornithine hydrochloride | 68278-23-9 | sc-252762A sc-252762 sc-252762B | 10 mg 25 mg 50 mg | $82.00 $173.00 $275.00 | 1 | |
DL-α-Difluoromethylornithine hydrochloride acts as a potent inhibitor of ornithine decarboxylase (ODC), showcasing distinctive molecular interactions that disrupt polyamine synthesis. Its difluoromethyl group enhances binding affinity to the enzyme, altering reaction kinetics and inhibiting substrate conversion. The compound's unique electronic properties influence its reactivity, while its solubility characteristics allow for effective integration into diverse chemical environments, impacting its overall behavior in biochemical pathways. | ||||||
(2S)-(+)-Amino-5-iodoacetamidopentanoic acid | 35748-65-3 | sc-202409 sc-202409A | 5 mg 25 mg | $209.00 $413.00 | ||
(2S)-(+)-Amino-5-iodoacetamidopentanoic acid serves as a selective inhibitor of ornithine decarboxylase (ODC), exhibiting unique structural features that facilitate specific enzyme interactions. The presence of the iodoacetamido group enhances its reactivity, allowing for targeted binding that modifies enzymatic activity. Its stereochemistry contributes to distinct conformational dynamics, influencing the kinetics of substrate interaction and altering metabolic pathways in a nuanced manner. | ||||||
Ornithine Decarboxylase Inhibitor, POB | sc-222102 | 10 mg | $182.00 | |||
Ornithine Decarboxylase Inhibitor, POB, is characterized by its ability to disrupt the catalytic function of ODC through competitive inhibition. Its unique structural motifs enable precise interactions with the enzyme's active site, leading to altered reaction kinetics. The compound's hydrophobic regions enhance binding affinity, while its specific stereochemical arrangement influences conformational stability, ultimately affecting downstream polyamine synthesis and cellular growth regulation. | ||||||
MDL 72527 | 93565-01-6 | sc-295375C sc-295375B sc-295375 sc-295375D sc-295375A | 1 mg 5 mg 10 mg 25 mg 50 mg | $45.00 $132.00 $201.00 $391.00 $750.00 | ||
This compound is a reversible and competitive inhibitor of ODC | ||||||
Caffeic Acid | 331-39-5 | sc-200499 sc-200499A | 1 g 5 g | $32.00 $62.00 | 1 | |
Caffeic Acid acts as an Ornithine Decarboxylase inhibitor by modulating enzyme activity through non-covalent interactions. Its phenolic structure allows for effective hydrogen bonding and π-π stacking with key residues in the active site, resulting in a decrease in substrate availability. The compound's antioxidant properties may also influence redox states within the cell, further impacting ODC activity and related metabolic pathways. Its solubility in various solvents enhances its accessibility for interaction with biological systems. | ||||||
(2S)-(+)-Amino-6-iodoacetamidohexanoic acid | 90764-56-0 | sc-220847 | 5 mg | $204.00 | ||
(2S)-(+)-Amino-6-iodoacetamidohexanoic acid functions as an Ornithine Decarboxylase inhibitor by engaging in specific electrostatic interactions with the enzyme's active site. The presence of the iodoacetamido group facilitates unique covalent modifications, altering enzyme conformation and reducing catalytic efficiency. Its structural features promote selective binding, influencing reaction kinetics and potentially modulating downstream metabolic pathways. The compound's hydrophilic nature enhances its solubility, allowing for effective interaction in diverse environments. | ||||||
Phenylethyl 3-methylcaffeate | 71835-85-3 | sc-205804 sc-205804A | 50 mg 100 mg | $100.00 $145.00 | ||
Phenylethyl 3-methylcaffeate functions as an Ornithine Decarboxylase inhibitor by engaging in specific hydrogen bonding and hydrophobic interactions with the enzyme's active site. The 3-methylcaffeate structure introduces steric hindrance, which can modulate enzyme conformation and activity. Additionally, its unique electronic properties may influence reaction kinetics, affecting the rate of substrate conversion. The compound's amphiphilic nature enhances its solubility in various environments, promoting diverse molecular interactions. | ||||||